Co-Organizers

Janet A. Englund, MD photo

Janet A. Englund, MD

Janet A. Englund, MD, is a professor in the Department of Pediatrics at the University of Washington School of Medicine and Seattle Children’s Hospital. Dr. Englund’s research interests include the study of the diagnosis, prevention, and treatment of viral respiratory diseases in children, pregnant women, and immunocompromised hosts. She studies new viral vaccines and novel methods of antiviral therapy for respiratory viruses including influenza, adenovirus, parainfluenza viruses, and respiratory syncytial virus (RSV). Dr. Englund has a longstanding interest in maternal immunization and was a co-investigator of maternal immunization with influenza virus vaccines in Nepal sponsored by the Bill and Melinda Gates Foundation, in collaboration with colleagues at Johns Hopkins University and Cincinnati Children’s Hospital, and RSV vaccines in Seattle. As a clinical associate at Fred Hutchinson Cancer Research Center, she is actively involved in transplant-related protocols with Drs. Michael Boeckh and Alpana Waghmare in studies of the prevention, treatment, and outcome of respiratory viral diseases in transplant recipients of all ages.

Dr. Englund’s research group at Seattle Children’s Hospital Research Institute is a member of the New Vaccine Surveillance Network of the Centers for Disease Control and Prevention (CDC). This group assesses vaccine effectiveness of rotavirus and influenza virus vaccines in population-based studies of healthy and sick children and is involved in epidemiological studies of other viruses including respiratory syncytial virus, rhinovirus, enterovirus D68, and norovirus. Dr. Englund and her research team are actively involved in studies of new respiratory vaccines and antivirals including vaccines for the prevention of RSV in infants, children, and pregnant women, and antivirals in healthy and immunocompromised children. Her group is also studying new methods to diagnose and characterize viral respiratory diseases in collaboration with investigators at the University of Washington.

Dr. Englund has participated in national and international organizations including lecturing at international vaccine courses such as the Advanced Course of Vaccinology, the American Academy of Pediatrics, the CDC-sponsored Advisory Committee on Immunization Practices, the Food and Drug Administration’s Vaccines and Related Biological Products Advisory Committee, and the maternal immunization safety group at the World Health Organization (WHO). She is past president of the Pediatric Infectious Diseases Society (PIDS), a past board member of the Infectious Diseases Society of America (IDSA) and the WHO Influenza Working Group, and a current member of the Publications Committee and Influenza Working Group of IDSA. She received the PIDS Distinguished Physician Award in 2015 and was the Caroline Breese Hall Lecturer in 2017.

Betsy C. Herold, MD photo

Betsy C. Herold, MD

Betsy C. Herold, MD, is professor of pediatrics and microbiology-immunology, vice chair for research in the Department of Pediatrics, and chief of the Division of Pediatric Infectious Diseases at Albert Einstein College of Medicine and the Children’s Hospital at Montefiore in the Bronx, N.Y. Dr. Herold is also the director of the Translational Prevention Research Center at Einstein. She graduated from the University of Pennsylvania Medical School, completed a residency in pediatrics, clinical fellowship in pediatric infectious diseases, and postdoctoral fellowship in herpes virology at Northwestern University. She leads a translational research program focused on understanding herpes simplex virus (HSV) entry and pathogenesis, the HIV-HSV syndemic, and exploiting that knowledge to develop safe and effective antiviral therapies. Her lab has played a key role in recognizing the role calcium signaling plays in facilitating HSV entry, shed light on molecular mechanisms by which HSV enhances HIV acquisition and persistence, and promoted the development of intravaginal rings to deliver drugs to protect women from HIV and HSV. Most recently, in collaboration with William R. Jacobs, PhD, their research teams have engineered an HSV-2 virus deleted in glycoprotein D as a novel vaccine candidate. They found that the vaccine strain is safe and elicits high titer non-neutralizing Fc receptor activating antibodies that completely protect mice and guinea pigs from primary disease and latency following vaginal or skin challenge with a diverse array of clinical isolates of HSV-1 and HSV-2.

Elaine I. Tuomanen

Elaine I. Tuomanen

Elaine I. Tuomanen, MD, CM, is the ALSAC Endowed Chair of Infectious Diseases at St. Jude Children’s Research Hospital in Memphis, Tennessee. She is also director of the Children’s Infection Defense Center at St. Jude and adjunct professor of pediatrics and molecular sciences at the University of Tennessee.

After receiving her medical degree from McGill University, she served as pediatric intern and resident at Montreal Children’s Hospital. Dr. Tuomanen began her pediatric infectious diseases fellowship training at the University of Virginia in Charlottesville and completed her training as the Bristol Fellow of Infectious Diseases and the Parker B. Francis Pulmonary Research Fellow at Rockefeller University, where she began her work on Streptococcus pneumoniae pathogenesis under the mentorship of Dr. Alexander Tomasz. While an associate professor at Rockefeller University, she headed the Laboratory of Molecular Infectious Diseases, where she continued her groundbreaking work on the interplay between pneumococci and innate immunity. Among her seminal contributions are studies that link pneumococcal virulence factors to specific host receptors, the inflammatory bioactivities of cell wall, and the increased susceptibility of children with sickle cell disease to pneumococcal disease. Her work has been continuously funded by the National Institutes of Health for 30 years, and she is the author of over 200 peer-reviewed publications and over 100 reviews and book chapters.

In recognition of her impact on medical sciences, Dr. Tuomanen was elected a member of the Association of American Physicians and fellow of the American Academy for Microbiology. She was the recipient of the 1998 Maxwell Finland Award from Infectious Diseases Society of America, the 1997 E. Mead Johnson Award for Outstanding Research in Pediatrics from the American Academy of Pediatrics and the inaugural Pediatric Infectious Diseases Society (PIDS) Distinguished Research Award in 2014.

Dr. Tuomanen has devoted many years to understanding the mechanisms by which Streptococcus pneumoniae invades the human host, establishes infection, and manifests as invasive disease. In recent work, she and her research group have identified the molecular mechanisms by which S. pneumoniae access the cerebrospinal fluid and have developed vaccine antigens that protect against S. pneumoniae colonization, pneumonia, and meningitis. In addition, she has demonstrated a strong commitment to educating and mentoring the research efforts of our younger colleagues as the founder of the annual St. Jude-PIDS ID Research Conference, initiating the St. Jude-PIDS Transplant ID Symposium, and creating the PIDS-St. Jude Fellowship Award in Basic Science.

Speakers/Moderators

Ami S. Bhatt, MD, PhD - photo

Ami S. Bhatt, MD, PhD

Ami S. Bhatt, MD, PhD, an assistant professor of medicine and genetics at Stanford University, is a physician scientist with a strong interest in microbial genomics and metagenomics. She received her MD and PhD from the University of California, San Francisco. She then completed her residency and fellowship training at Harvard University’s Brigham and Women’s Hospital and Dana-Farber Cancer Institute, and served as chief medical resident from 2010-2011. She joined the faculty of the Departments of Medicine (Divisions of Hematology and Bone Marrow Transplantation) and Genetics at Stanford University in 2014 after completing a post-doctoral fellowship focused on genomics at the Broad Institute of Harvard and the Massachusetts Institute of Technology. Dr. Bhatt is a current Damon Runyon Clinical Investigator and has received multiple awards for her academic scholarship including the Chen Award of Excellence from the Human Genome Organisation (HUGO).

Her team’s research program seeks to illuminate the interplay between the microbial environment and host/clinical factors in human diseases. Her translational laboratory develops and applies novel molecular and computational tools to study strain level dynamics of the microbiome, to understand how microbial genomes change over time and predict the functional output of microbiomes. These innovations facilitate much improved (1) measurement of the types and functions of microbes in patients with non-communicable diseases, (2) understanding of the interactions between microbial genes, gene products, and host cells, and (3) testing of the impact of microbially targeted interventions in clinical trials.

In addition to carrying out research at Stanford University, Dr. Bhatt has active collaborations world-wide including in Nigeria and South Africa. She is committed to ensuring that advances in research touch the lives of individuals in all income settings—and thus, in her spare time, enjoys volunteering for the nonprofit she co-founded, Global Oncology.

Buddy Creech, MD, MPH - photo

C. Buddy Creech, MD, MPH

C. Buddy Creech, MD, MPH, is associate professor of pediatric infectious diseases at Vanderbilt University School of Medicine and Monroe Carell Jr. Children’s Hospital at Vanderbilt, and director of the Vanderbilt Vaccine Research Program. Dr. Creech’s research focuses on the evaluation of new vaccines and immunotherapeutics, including candidate vaccines for influenza, pertussis, and S. aureus, and using systems biology tools to characterize the circulating and tissue-specific immune response to vaccination. He also has a longstanding interest in defining the clinical and molecular epidemiology of S. aureus colonization and disease in children, particularly among children with musculoskeletal infections. Dr. Creech is principal investigator of the National Institutes of Health-funded Vanderbilt Vaccine and Treatment Evaluation Unit and co-principal investigator for the Centers for Disease Control and Prevention-funded Clinical Immunization Safety Assessment site at Vanderbilt. He serves as secretary-treasurer on the Board of Directors of the Pediatric Infectious Diseases Society (PIDS) and is chair of the PIDS Research Affairs Committee.

Dana Danino, MD - photo

Dana Danino, MD

Dana Danino, MD, completed her clinical fellowship in pediatric infectious diseases in 2017 at Soroka University Medical Center in Israel and since then has worked as a pediatric infectious diseases physician treating patients with underlying malignancies and primary immunodeficiencies. Currently, she is completing a Pediatric Infectious Diseases Host Defense Fellowship at Nationwide Children’s Hospital in Columbus, Ohio. Dr. Danino’s recent research focuses on the vaccination of children after hematopoietic stem cell transplant. She is also involved in the formulation of clinical practice guidelines for the prevention and management of infections in pediatric hematopoietic stem cell transplant recipients.

Jay A. Fishman, MD - photo

Jay A. Fishman, MD

Jay A. Fishman, MD, is professor of medicine at Harvard Medical School, director of the Transplant Infectious Diseases and Compromised Host Program at Massachusetts General Hospital (MGH), and associate director of the MGH Transplant Center. Dr. Fishman completed medical school at Johns Hopkins University School of Medicine, internal medicine training and an infectious disease fellowship at MGH, and fellowships in molecular biology and genetics at MGH and Harvard Medical School. Dr. Fishman is a fellow of the American College of Physicians, the American Society of Transplantation, and the Infectious Diseases Society of America. Dr. Fishman established the Transplant and Immunocompromised Host Program at MGH, which has trained many of the leaders in this field worldwide. His background in immunology, molecular biology, and infectious diseases provides a unique translational approach to transplantation infectious disease. His laboratory investigates infections in xenotransplantation and viral pathogenesis in transplantation. He has a special interest in molecular diagnostics and biotechnology and in medical education. Dr. Fishman has over 300 publications and is a frequent contributor at international symposia. He is past-president of the American Society of Transplantation. He has received career achievement awards from the American Society of Transplantation and the Transplantation Society.

Hayley Gans photo

Hayley Gans, MD

Hayley Gans, MD, is a professor of pediatrics at Stanford University Medical Center. She spends her clinical time on the pediatric infectious diseases service and co-directs the Pediatric Infectious Diseases Program for Immunocompromised Hosts. She is also the director of fellowship education for the Department of Pediatrics and the associate program director for the Pediatric Infectious Diseases Program. The focus of her research has involved investigations into the innate and adaptive immunity to viral vaccines in several different populations. Initial studies included infants receiving an early measles vaccination regimen, which then expanded to include preterm infants, HIV-infected adults and children, and children and adults undergoing liver and renal transplantation. In addition, studies also included an expanded repertoire of viral antigens, such as cytomegalovirus, poliovirus, varicella, and mumps. Recently, she has expanded her research to address viral infections in pediatric solid organ transplant recipients. Additional research efforts are directed at bioinformatics in immunocompromised cohorts and outcome measures in ambulatory pediatrics, as well as studies in the arena of medical education.

Abby M. Green, MD - photo

Abby M. Green, MD

Abby M. Green, MD, is an instructor in the Division of Pediatric Infectious Diseases and the Division of Oncology at the Children’s Hospital of Philadelphia. Her clinical time is spent attending on the immunocompromised ID service and in an outpatient clinic dedicated to managing infectious complications in oncology and hematopoietic stem cell transplantation patients. Dr. Green’s laboratory research is focused on the etiology of DNA damage in pediatric cancer. Beginning in July 2019, Dr. Green will be an assistant professor of pediatrics at Washington University in St. Louis, where she will be a part of the newly-established immunocompromised ID service at St. Louis Children’s Hospital.

Michael D. Green, MD, MPH photo

Michael Green, MD, MPH

Michael Green, MD, MPH, is professor of pediatrics, surgery, and clinical and translational science at the University of Pittsburgh School of Medicine. He received his medical degree from the University of Illinois in Chicago and his master’s degree from the University of Pittsburgh. He completed a pediatric residency and a fellowship in pediatric infectious diseases at Children’s Hospital of Pittsburgh.

Throughout his career, Dr. Green’s clinical and research interests have focused on the prevention and treatment of infections in immunocompromised children with a particular interest in the care of children undergoing solid organ transplantation. Among his professional affiliations, he is a member of the Pediatric Infectious Diseases Society, the American Pediatric Society, the Infectious Diseases Society of America, the International Pediatric Transplant Association, and the American Society of Transplantation. Dr. Green has published more than 135 peer-reviewed articles, has been invited to author over 45 publications, and has written more than 70 review articles or textbook chapters. He serves as an associate editor for both Pediatric Transplantation and the Journal of the Pediatric Infectious Diseases Society. He was co-editor of the first edition of the Guidelines for the Prevention and Management of Infectious Complications of Solid Organ Transplantation, published by the American Society of Transplantation, and is currently editor-in-chief of the upcoming fourth edition, which is in development. He currently serves on the Pediatric Infectious Diseases Sub Board of the American Board of Pediatrics and is a member of the Food and Drug Administration’s Antimicrobial Advisory Committee. He has participated in numerous consensus conference and guideline working groups relating to the field of transplant infectious diseases and previously served as chair of the Organ Procurement and Transplantation Network/United Network for Organ Sharing Ad Hoc Disease Transmission Advisory Committee. An active teacher and clinical researcher, Dr. Green has been invited to present his work at national and international conferences, and has consistently received grant funding for his work since 1987.

Benjamin Hanisch, MD - photo

Benjamin Hanisch, MD

Benjamin Hanisch, MD, is a specialist in pediatric infectious diseases and director of the Transplant Infectious Disease Program at Children’s National Health System in Washington, D.C. His research and clinical interests include infections in immunocompromised patients, particularly those who have received solid organ or blood and marrow transplantation. Dr. Hanisch is also an assistant professor of pediatrics at the George Washington University School of Medicine and Health Sciences.

Randall T. Hayden, MD - photo

Randall T. Hayden, MD

Randall T. Hayden, MD, is director of Clinical Pathology Laboratories, director of Clinical and Molecular Microbiology, and a member of the Department of Pathology at St. Jude Children’s Research Hospital in Memphis. His research interests focus on the application of molecular methods to diagnostic challenges in clinical microbiology, with particular emphasis on the diagnosis of infections in the immunocompromised host. He is editor-in-chief of Diagnostic Microbiology of the Immunocompromised Host, 2nd Edition; co-editor of Molecular Microbiology, Diagnostic Principles and Practice, 3rd Edition, and of Medically Important Fungi, 6th Edition; and section editor for the Manual of Clinical Microbiology, 12th Edition, all from the American Society for Microbiology Press. He serves as editor of the journal Clinical Microbiology Reviews and associate editor for the Journal of Clinical Virology. He is president of the Pan American Society for Clinical Virology (PASCV) and co-chair of the PASCV Molecular Virology Workshop.

Sarah M. Heston, MD - photo

Sarah M. Heston, MD

Sarah M. Heston, MD, originally from Memphis, attended the University of Tennessee Health Science Center College of Medicine in Memphis for medical school and was a pediatric resident and chief resident at Le Bonheur Children’s Hospital. Dr. Heston moved to Durham, N.C., to start her pediatric ID fellowship at Duke University in 2018.

Marian G. Michaels, MD, MPH

Marian G. Michaels, MD, MPH, is a professor of pediatrics and surgery in the Division of Pediatric Infectious Diseases at the University of Pittsburgh School of Medicine and Children’s Hospital of Pittsburgh, where she is co-director of Pediatric Transplant Infectious Diseases. Starting in fellowship and throughout Dr. Michaels’ career, she has been actively involved in research and clinical work with immunocompromised hosts, particularly those who have undergone solid organ transplantation. Dr. Michaels currently chairs the Organ Procurement and Transplantation Network/United Network for Organ Sharing Ad Hoc Disease Transmission Advisory Committee and serves on the board of the American Society of Transplantation.

Lillian Sung, MD, PhD - photo

Lillian Sung, MD, PhD

Lillian Sung, MD, PhD, is a full professor and senior scientist at The Hospital for Sick Children in Toronto, Ontario, Canada. She is certified in the specialties of pediatrics, infectious diseases, hematology, and clinical investigation. She completed a PhD in clinical epidemiology at the University of Toronto in 2004. She has a clinical research program focused on supportive care for children with cancer. Her methodological focus is on randomized and observational trials, meta-analysis, and patient-reported outcomes. She is the principal investigator on multiple operating grants from the National Institutes of Health (NIH), Canadian Cancer Society Research Institute, and the Canadian Institutes of Health Research. Dr. Sung is the co-principal investigator on the NCI Community Oncology Research Program (NCORP) Research Base grant, which supports the Cancer Control and Supportive Care Program within the Children’s Oncology Group. She is also the co-principal investigator on an NIH R25 grant to support the Clinical Research Training Institute, sponsored by the American Society of Hematology.

Jason B. Weinberg, MD - photo

Jason B. Weinberg, MD

Jason B. Weinberg, MD, completed his undergraduate education at Princeton University in 1992 and received his MD from Duke University in 1996. He completed a residency in pediatrics at the Children’s Hospital Colorado/University of Colorado Health Sciences Center in 1999 and served as chief resident in pediatrics from 1999 to 2000. After fellowship training in pediatric infectious diseases at the University of Michigan, he remained at the University of Michigan, where he is an associate professor of pediatrics and communicable diseases and associate professor of microbiology and immunology. He is the program director for the Pediatric Infectious Diseases Fellowship Program and the associate director of fellowship programs for the Department of Pediatrics. Dr. Weinberg is active in patient care, with interests in clinical virology and immunocompromised hosts. Research in Dr. Weinberg’s laboratory is focused on studies of adenovirus pathogenesis.