Vanderbilt University Medical Center

D-7235 MCN, 1161 21st Avenue South
Nashville
TN
37232-2581
USA
Phone: (615) 322-2250
Fax: (615) 343-9723

DIVISION LEADERSHIP

TRAINING PROGRAM DIRECTOR: Ritu Banerjee, MD, PhD
RESEARCH INTEREST: Antimicrobial stewardship; implementation and outcomes using rapid diagnostics for infectious diseases

TRAINING PROGRAM ASSOCIATE PROGRAM DIRECTOR: Isaac Thomsen, MD, MSCI
RESEARCH INTEREST: Studies of the immune response to Staphylococcus aureus disease in children; Osteomyelitis and septic arthritis: Studies of epidemiology and optimal clinical practice

DIVISION CHIEF: Mark Denison, MD
RESEARCH INTEREST: Emerging respiratory viruses; antiviral development

CLINICAL SERVICES DIRECTOR: Kathryn Edwards, MD
RESEARCH INTERESTS: Evaluation of new vaccines for prevention of infectious diseases in adults and children; epidemiology of infections in children

FACULTY MEMBERS

ASSOCIATE PROFESSOR: C. Buddy Creech, MD, MPH
RESEARCH INTEREST: Director, Vanderbilt Vaccine Research Program; staphylococcal infections and vaccine development, bone and joint infections, influenza, and clinical trials of new antimicrobial therapies.

ASSOCIATE PROFESSOR: Natasha Halasa, MD, MPH
RESEARCH INTEREST: Vaccine studies in specialized populations; diarrheal and respiratory illness surveillance

ASSOCIATE PROFESSOR: Troy D. Moon, MD, MPH
RESEARCH INTEREST: Global medical and public health training/capacity building; HIV implementation science; emerging infections

ASSOCIATE PROFESSOR: Gregory Wilson, MD
RESEARCH INTEREST: Director, Vanderbilt Pediatric & Adolescent HIV/AIDS Clinic, a TN Pediatric AIDS Center of Excellence; HIV vaccine trials; infection control and prevention

ASSISTANT PROFESSOR: James E. Cassat, MD, PhD
RESEARCH INTEREST: Clinical care of children with musculoskeletal infections; basic research laboratory focused on understanding the pathogenesis of staphylococcal osteomyelitis

ASSISTANT PROFESSOR: Daniel Dulek, MD
RESEARCH INTEREST: Infections in immunocompromised patients; transplant infectious diseases; immunodeficiency; parasitology, medical education

ASSISTANT PROFESSOR: Leigh Howard, MD, MPH
RESEARCH INTEREST: Vaccine-preventable infections in developing countries; viral and bacterial respiratory disease surveillance; infections in immunocompromised hosts

INSTRUCTOR: James Carlucci, MD, MPH
RESEARCH INTEREST: Pediatric HIV health services improvement and implementation research in low-resource settings; clinical care of children exposed to or infected with HIV, Hepatitis C, and other infectious diseases


 

MAJOR FEATURES OF TRAINING PROGRAM:
The Pediatric Infectious Diseases Fellowship program is a three-year ACGME-accredited program designed to prepare fellows for fulfilling careers in infectious diseases, tailored to the individual aspirations of the trainee. One year is dedicated to clinical training. Responsibilities on the clinical service include the evaluation and management of children admitted to the Monroe Carell Jr. Children's Hospital at Vanderbilt, as well as outpatient consultations in the Pediatric Infectious Diseases Clinic, the Pediatric HIV clinic, the local county health department tuberculosis clinic, and the Pediatric Emergency Department. Two years are focused on research training. Projects may include global health, outcomes research, clinical research, public health, and laboratory research and may be conducted within the division or in collaboration with other departments at Vanderbilt. The training program provides outstanding research and clinical experiences, including in infection control and antimicrobial stewardship.


AFFILIATED HOSPITALS: Monroe Carell Jr. Children’s Hospital at Vanderbilt

Monroe Carell Jr. Children’s Hospital at Vanderbilt is one of the nation’s leading children’s hospitals. With more than 400 physicians trained in 30 pediatric and surgical specialties, we’re equipped to handle any issue a child may face – from the simple to the complex. The Children’s Hospital at Vanderbilt opened its doors in 2004 and consists of eight floors and 835,219 square feet. Children’s Hospital is readying for additional growth that will add four floors and 160,000 total square feet. In 2017, there were 325,233 children seen in clinics. The Emergency Department saw 52,183 children. There were 15,977 inpatient discharges at Children's Hospital. Total Inpatient Beds 267, Intensive Care Beds 42, Neonatal Intensive Care Unit beds 96, Emergency Department Beds 96, Acute Care Beds 129, and Operating Rooms 18. Children’s Hospital is a nationally recognized provider of pediatric health care services. We are the only pediatric hospital in Tennessee ranked in 10 out of 10 pediatric specialty programs in U.S. News & World Report magazine’s 2017-2018 “Best Children’s Hospitals.” Children’s Hospital is also ranked 13th in the nation by Parents magazine and recognized by Leapfrog as one of nine top children’s hospitals in the nation.

FELLOWS ACCEPTED EACH YEAR: Two

TRAINING FOR MD; DO; MD, PhD: Yes

FUNDING IS ENSURED FOR ALL 3 YEARS: Yes

VISAS ACCEPTED: J1, H1B, Other

IS COMPLETION OF PEDIATRIC RESIDENCY TRAINING IN THE U.S. OR CANADA A REQUIREMENT? No

THE PROGRAM OFFERS THE FOLLOWING TRAINING:

Program provides training in diagnostic microbiology using laboratories on site:

  • Microbiology laboratory: Yes
  • Clinical virus isolation laboratory: Yes
  • Molecular diagnostics: Yes

Program provides training in infection control and hospital epidemiology as:

  • Didactic lectures: Yes
  • Hands on experience: Yes
  • Infection Control Meetings/Membership: Yes

Opportunity to fulfill the ABP requirements for scholarly activity is available in the following general areas:

  • Bacteriology/bacterial infections: Yes
  • Epidemiology and statistics: Yes
  • Infection control/hospital epidemiology: Yes
  • Immunizations/Public health: Yes
  • Mycology/fungal infections: No
  • Parasitology/parasitic diseases: Yes/Malaria
  • Virology/viral diseases: Yes
  • Antimicrobial agents: Yes

Research opportunities in the section’s program could be describes as:
This division has one of the broadest research portfolios of any in the country.

  • Basic (bench): Yes
  • Molecular: Yes
  • Translational: Yes
  • Epidemiologic: Yes
  • Clinical: Yes
  • International/Public Health: Yes
  • Health Services: Yes
  • HIV, Basic: Yes
  • HIV, Clinical: Yes
  • ACTG Site: Yes
  • Other: Computational

Documented liaison exists offering opportunities for research experience in the laboratory of investigator(s) who is (are) not faculty of the section: Yes

Program offers the opportunity to obtain a Master’s degree in a field such as Public Health, Education, Clinical Sciences, or Epidemiology (assuming appropriate arrangements are made): Yes, MPH or MSCI

Graduate school courses are available to trainee (assuming appropriate arrangements are made): Yes

Program provides substantial clinical experiences for trainees in special areas/hosts:

  • HIV: Yes
  • Bone marrow transplantation: Yes
  • Solid organ/transplantation: Yes
  • Travelers/adoptees: Yes
  • Adults: Yes
  • Congenital immune deficiencies: Yes

Program includes ABP-required core curricula in scholarly activities in didactic lecture course for fellows (includes epidemiology, statistics, research design, and academic careers): Yes

Program has an NIH-sponsored training grant: Yes

The Infectious Diseases Service is the primary care provider for HIV-infected children and adolescents: Yes

Average number of new outpatient consultations per month: 35

Average number of established outpatient follow-up visits per month: 77

Average number of new inpatient consultations per month: 28

Number of trainees completing program in the last 5 years: (2013-2018) 9


TITLES OF RECENT FELLOWS’ PUBLISHED PAPERS OR RESEARCH PROJECTS:

Carlucci JG, Halasa N, Creech CB, Dulek DE, Gómez-Duarte OG, Nelson GE, Talbot HK, Scalise ML, Scott PL, Mahadevan U, Beaulieu DB. Vertical Transmission of Histoplasmosis Associated With Anti-Tumor Necrosis Factor Therapy. J Pediatric Infect Dis Soc. 2016 Jun. PMID: 27012275.

Carlucci JG, Moon TD. Children, care and treatment. Book chapter - Encyclopedia of AIDS (Editors: Hope TJ, Stevenson M, Richman D) New York, NY: Springer 2016:1-10.

Carlucci JG, Blevins Peratikos M, Cherry CB, Lopez ML, Green AF, González-Calvo L, Moon TD, the Ogumaniha-SCIP Zambézia Consortium. Prevalence and determinants of Malaria among children in Zambézia Province, Mozambique. Malaria J. 2017 Mar. PMID: 28274257; PMCID: PMC5343407.

Carlucci JG, Blevins M, Kipp AM, Lindegren ML, Du QT, Renner L, Reubenson G, Ssali J, Yotebieng M, Mandalakas AM, Davies MA, Ballif M, Fenner L, Pettit AC, the International Epidemiology Databases to Evaluate AIDS (IeDEA) Network. Tuberculosis treatment outcomes among HIV/TB co-infected children in the International Epidemiology Databases to Evaluate AIDS (IeDEA) network. J Acquir Immune Defic Syndr. 2017 Jun. PMID: 28234689.

Qian HZ, Hu Y, Carlucci JG, Yin L, Li X, Giuliano AR, Li D, Gao L, Shao Y, Vermund SH. Human Immunodeficiency Virus Status Differentially Associated With Genital and Anal Human Papillomavirus Infection Among Chinese Men Who Have Sex With Men: A Cross-Sectional Survey. Sexually Transmitted Diseases. 2017 Nov. PMID: 28876311.

Carlucci JG, Farooq SA, Sizemore L, Rickles M, Cosley B, McCormack L, Wester C. Low hepatitis C antibody screening rates among an insured population of Tennessean Baby Boomers. PLoS One. 2017 Nov. PMID: 29190748.

Wood JB, Thomsen IP, Creech CB, Newland JG. Best Practices for Treatment of Invasive Methicillin-Susceptible Staphylococcus aureus Infections: The Case for Oxacillin. J Pediatric Infect Dis Soc. 2016 Dec;5(4):480-482. PMID: 27609072.

Thomsen IP, Sapparapu G, James DBA, Cassat JE, Nagarsheth M, Kose N, Putnam N, Boguslawski KM, Jones LS, Wood JB, Creech CB, Torres VJ, Crowe JE Jr. Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action. J Infect Dis. 2017 Apr. PMID: 28186295.

An TJ, Benvenuti MA, Mignemi ME, Martus J, Wood JB, Thomsen IP, Schoenecker JG. Similar Clinical Severity and Outcomes for Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Pediatric Musculoskeletal Infections. Open Forum Infect Dis. 2017 Feb. Open Forum Infect Dis. 2017 Feb

Wood JB, Jones LS, Soper NR, Nagarsheth M, Creech CB, Thomsen IP. Commercial Intravenous Immunoglobulin Preparations Contain Functional Neutralizing Antibodies against the Staphylococcus aureus Leukocidin LukAB (LukGH). Antimicrob Agents Chemother. 2017 Oct 24;61(11). PMID: 28874371

Wood J, Jones LJ, Soper NS, Xu M, Torres VJ, Creech CB, Thomsen I.  Serologic Detection of Antibodies Targeting the Leukocidin LukAB Strongly Predicts Staphylococcus aureus in Children with Musculoskeletal Infections.  Journal of the Pediatric Infectious Diseases Society, 2018 Jan.

Wood JB, Fricker GP, Buddy Creech C. Practice Patterns of Providers for the Management of Staphylococcus aureus Bacteremia in Children: Results of an Emerging Infections Network Survey. J Pediatric Infect Dis Soc. 2018 Mar 8. PMID: 29534244

Fraizer B, Katz SE, Wood J, Cassat J. Resident Rounds: An Unusual Source of Sepsis in Two Previously Healthy Children. Clinical Pediatrics, 2017. PMID: 29084446

Katz, SE, Williams, DJ. Diagnostic and Therapeutic Challenges and Solutions for Community-Acquired Pneumonia in the Twenty First Century. Infectious Diseases Clinics of North America, 2017. PMID: 29269189


GRANT FUNDING RECEIVED FOR FELLOW RESEARCH PROJECTS:

James Carlucci, MD, MPH, 2015-2017, T32HD060554 NICHD Conducting Child Health Care Research in Vulnerable Populations grant, PI: William Cooper

James Wood, MD, 2015-2017, T32A1095202 NIAID Childhood Infections Research Program (ChIRP) grant, PI: Mark Denison

Sophie Katz, MD, 2017-2019, T32A1095202 NIAID Childhood Infections Research Program (ChIRP) grant, PI: Mark Denison

Sophie Katz, MD, 2017-2019, UL1TR002243 NCATS/NIH Center for Advancing Translational Sciences (CTSA) Award No, PI: Sophie Katz

Matthew Vogt, MD, PhD, 2017-2020, Pediatric Infectious Diseases Society – St. Jude Children’s Research Hospital Fellowship Program in Basic Research – Competitive research grant awarded annually to a single incoming Fellow in Pediatric Infectious Disease

Keerti Dantuluri, MD, 2018-2020, T32A1095202 NIAID Childhood Infections Research Program (ChIRP) grant, PI: Mark Denison

Varvara Probst, MD, 2018-2020, T32HD060554 NICHD Conducting Child Health Care Research in Vulnerable Populations grant, PI: William Cooper