University of Tennessee Health Science Center/St. Jude Children's Research Hospital

262 Danny Thomas Place, MS 320
Phone: (901) 595-3486
Fax: (901) 595-3099


  • Vaccine design and evaluation
  • Epidemiology and therapy of infections in the immunocompromised host
  • Quality improvement

St. Jude Children's Research Hospital - Elaine I. Tuomanen, MD

  • Molecular pathogenesis of Streptococcus pneumoniae invasion and inflammation

LeBonheur Children's Hospital - Sandra Arnold, MD

  • Antibiotic stewardship
  • Clinical trials
  • Pneumonia
  • Osteomyelitis


  • Bindiya Bagga, MD
    • Respiratory viruses
    • Mucosal Immune Responses
    • Molecular Diagnostics
    • Antimicrobial Stewardship
  • Miguela Caniza, MD
    • International outreach
    • Infection control in pediatric hematology/oncology services in countries of limited resources
  • John DeVincenzo, MD
    • Immunoprophylaxis
    • Immunotherapies and pathogenesis of respiratory syncytial virus and genetic determinants of immune response
    • Tropical infectious diseases
  • Patricia M. Flynn, MD
    • Infections in immunocompromised hosts (mycotic infections and intravascular catheter infections)
    • HIV/AIDS
  • Aditya H. Gaur, MD
    • Diagnosis and treatment of infections in immunocompromised children
    • Pediatric HIV infection
  • Hans Haecker, MD, PhD
    • Signal transduction of members of the Toll-like receptor family and TNF receptor family
    • Regulation of the innate immune response in infectious disease
  • Hana Hakim, MD
    • Infection control
    • Risk stratification of febrile neutropenic children with cancer
  • Julia L. Hurwitz, PhD
    • Paramyxovirus
    • HIV vaccine design
  • Suzanne Jackowski, PhD
    • Bacteria lipid metabolism
  • Akinobou Kamei, MD
    • Innate and adaptive immunity to Pseudomonas aeruginosa
    • Development of new preventive/therapeutic strategies for infectious diseases in neutropenic cancer patients
  • Katherine M. Knapp, MD
    • Pediatric and adolescent HIV/AIDS
    • Fungal infections in immunocompromised patients
  • Gabriela Maron, MD
    • Fungal infections in immunocompromised patients
    • Dengue virus infections
    • Pediatric and adolescent HIV/AIDS
  • Jonathan McCullers, MD
    • Pathogenesis and evolution of influenza viruses, therapy for influenza infection
  • Peter J. Murray, PhD
    • Cytokine regulation of immunse system and genetic manipulation of mycobacteria
  • Charles O. Rock, PhD
    • Membrane fatty acid and phospholipid synthesis in bacteria
    • Development of neovel antibacterial therapeutics
  • Jason Rosch, PhD
    • Bacterial genomics and metal transport
  • Charles J. Russell, PhD
    • Viral replication and vaccine design
  • Stacey Schultz-Cherry, PhD
    • Influenza virus and astrovirus pathogenesis
  • Richard J. Webby, PhD
    • Influenza pathogenesis and vaccine design


Wolf J, Curtis N, Worth LJ, Flynn PM. Central Line-associated Bloodstream Infection in Children: An Update on Treatment. Pediatr Infect Dis J. 2013 Aug;32(8):905-910. PubMed PMID: 23856714.

DeVincenzo JP, Guyton C, Rea H, Elmore E, Patel S, Wynn L, Harrison L, El Saleeby CM, Bagga B. Molecular detection and quantification of pertussis and correlation with clinical outcomes in children. Diagn Microbiol Infect Dis. 2013 May;76(1):10-5. doi: 10.1016/j.diagmicrobio.2012.12.015. Epub 2013 Mar 11. PubMed PMID: 23490009.

Minniear TD, Gaur AH, Thridandapani A, Sinnock C, Tolley EA, Flynn PM. Delayed entry into and failure to remain in HIV care among HIV-infected adolescents. AIDS Res Hum Retroviruses. 2013 Jan;29(1):99-104. doi: 10.1089/AID.2012.0267. Epub 2012 Nov 7. PubMed PMID: 23033848.

Wolf J, Shenep JL, Clifford V, Curtis N, Flynn PM. Ethanol lock therapy in pediatric hematology and oncology. Pediatr Blood Cancer. 2013 Jan;60(1):18-25. doi: 10.1002/pbc.24249. Epub 2012 Aug 21. Review. PubMed PMID: 22911535.

Carr S. Seasonal and pandemic influenza: an overview with pediatric focus. Adv Pediatr. 2012;59(1):75-93. doi: 10.1016/j.yapd.2012.04.016. Review. PubMed PMID: 22789575.

Carr SB, Adderson EE, Hakim H, Xiong X, Yan X, Caniza M. Clinical and demographic characteristics of seasonal influenza in pediatric patients with cancer. Pediatr Infect Dis J. 2012 Nov;31(11):e202-7. doi: 10.1097/INF.0b013e318267f7d9. PubMed PMID: 22772169; PubMed Central PMCID: PMC3473140.

Hakim H, Apiwattanakul N, Miyairi I, Arnold S. Blastomycosis: the great mimicker. Clin Pediatr (Phila). 2011 Dec;50(12):1156-60. doi: 10.1177/0009922811388513. PubMed PMID: 22121141.

Carr S, Allison KJ, Van De Velde LA, Zhang K, English EY, Iverson A, Daw NC, Howard SC, Navid F, Rodriguez-Galindo C, Yang J, Adderson EE, McCullers JA, Flynn PM. Safety and immunogenicity of live attenuated and inactivated influenza vaccines in children with cancer. J Infect Dis. 2011 Nov 15;204(10):1475-82. doi: 10.1093/infdis/jir561. Epub 2011 Sep 23. PubMed PMID: 21949042.

Naeem F, Rubnitz JE, Hakim H. Isolated nasal septum necrosis caused by Aspergillus flavus in an immunocompromised child. Pediatr Infect Dis J. 2011 Jul;30(7):627-9. doi: 10.1097/INF.0b013e31820b7c3a. PubMed PMID: 21245776.

Marón GM, Escobar GA, Hidalgo EM, Clara AW, Minniear TD, Martinez E, Pleites EB. Characterization of dengue shock syndrome in pediatric patients in El Salvador. Pediatr Infect Dis J. 2011 May;30(5):449-50. doi: 10.1097/INF.0b013e318212ab8e. PubMed PMID: 21490492.

Carr S, Ilyushina NA, Franks J, Adderson EE, Caniza M, Govorkova EA, Webster RG. Oseltamivir-resistant influenza A and B viruses pre- and postantiviral therapy in children and young adults with cancer. Pediatr Infect Dis J. 2011 Apr;30(4):284-8. doi: 10.1097/INF.0b013e3181ff863b. PubMed PMID: 21048522; PubMed Central PMCID: PMC3070406.

Bagga B, Shenep JL. Management of infections caused by vancomycin-resistant gram-positive bacteria. Pediatr Infect Dis J. 2010 Jul;29(7):662-4. doi: 10.1097/INF.0b013e3181e78efc. Review. PubMed PMID: 20574403.

Marón G, Gaur AH, Flynn PM. Antiretroviral therapy in HIV-infected infants and children. Pediatr Infect Dis J. 2010 Apr;29(4):360-3. doi: 10.1097/INF.0b013e3181d616d8. PubMed PMID: 20351530.

Marón GM, Clará AW, Diddle JW, Pleités EB, Miller L, Macdonald G, Adderson EE. Association between nutritional status and severity of dengue infection in children in El Salvador. Am J Trop Med Hyg. 2010 Feb;82(2):324-9. doi: 10.4269/ajtmh.2010.09-0365. PubMed PMID: 20134012; PubMed Central PMCID: PMC2813176.

Srinivasan A, Seifried S, Zhu L, Srivastava DK, Flynn PM, Bankowski MJ, Shenep JL, Hayden RT. Staphylococcus aureus bacteremia in pediatric patients with cancer. Pediatr Infect Dis J. 2010 Feb;29(2):172-4. doi: 10.1097/INF.0b013e3181b9a363. PubMed PMID: 19918212.

Gaur AH, Bagga B, Barman S, Hayden R, Lamptey A, Hoffman JM, Bhojwani D, Flynn PM, Tuomanen E, Webby R. Intravenous zanamivir for oseltamivir-resistant 2009 H1N1 influenza. N Engl J Med. 2010 Jan 7;362(1):88-9. doi: 10.1056/NEJMc0910893. Epub 2009 Dec 23. PubMed PMID: 20032317.

Srinivasan A, Seifried S, Zhu L, Bitar W, Srivastava DK, Shenep JL, Bankowski MJ, Flynn PM, Hayden RT. Short communication: methicillin-resistant Staphylococcus aureus infections in children and young adults infected with HIV. AIDS Res Hum Retroviruses. 2009 Dec;25 (12):1219-24. doi: 10.1089/aid.2009.0040. PubMed PMID: 20001313; PubMed Central PMCID: PMC2858900.

Srinivasan A, Seifried S, Zhu L, Srivastava DK, Flynn PM, Shenep JL, Bankowski MJ, Hayden RT. Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus infections in children with cancer. Pediatr Blood Cancer. 2009 Dec 15;53(7):1216-20. doi: 10.1002/pbc.22254. PubMed PMID: 19731325; PubMed Central PMCID: PMC3075015.

Caniza MA, Dueñas L, Lopez B, Rodriguez A, Maron G, Hayden R, Srivastava DK, McCullers JA. A practical guide to alcohol-based hand hygiene infrastructure in a resource-poor pediatric hospital. Am J Infect Control. 2009 Dec;37(10):851-4. doi: 10.1016/j.ajic.2009.05.009. Epup. PubMed PMID: 19796845.

Minniear TD, Buckingham SC. Managing Rocky Mountain spotted fever. Expert Rev Anti Infect Ther. 2009 Nov;7(9):1131-7. doi: 10.1586/eri.09.94. Review. PubMed PMID: 19883333.

Minniear TD, Gilmore B, Arnold SR, Flynn PM, Knapp KM, Gaur AH. Implementation of and barriers to routine HIV screening for adolescents. Pediatrics. 2009 Oct;124(4):1076-84. doi: 10.1542/peds.2009-0237. Epub 2009 Sep 14. PubMed PMID:19752084.

Srinivasan A, Wickes BL, Romanelli AM, Debelenko L, Rubnitz JE, Sutton DA, Thompson EH, Fothergill AW, Rinaldi MG, Hayden RT, Shenep JL. Cutaneous infection caused by Macrophomina phaseolina in a child with acute myeloid leukemia. J Clin Microbiol. 2009 Jun;47(6):1969-72. doi: 10.1128/JCM.02397-08. Epub 2009 Apr 22. PubMed PMID: 19386841; PubMed Central PMCID: PMC2691108.

Srinivasan A, Kleiman MB, Debelenko L, Stokes DC, De Vincenzo J, Wheat JL. False-negative Histoplasma antigen in acute pulmonary histoplasmosis: the value of urinary concentration by ultrafiltration and heat denaturation of serum proteins in detection of Histoplasma antigen. Pediatr Infect Dis J. 2009 May;28(5):447-9. doi: 10.1097/INF.0b013e318193ecc1. PubMed PMID: 19295461.

Caniza MA, Maron G, McCullers J, Clara WA, Cedillos R, Dueñas L, Arnold S, Williams BF, Tuomanen EI. Planning and implementation of an infection control training program for healthcare providers in Latin America. Infect Control Hosp Epidemiol. 2007 Dec; 28(12):1328-33. Epub 2007 Oct 22. PubMed PMID: 17994511.

Caniza MA, Clara W, Maron G, Navarro-Marin JE, Rivera R, Howard SC, Camp J, Barfield RC. Establishment of ethical oversight of human research in El Salvador: lessons learned. Lancet Oncol. 2006 Dec;7(12):1027-33. Review. PubMed PMID: 17138224.


Apiwattanakul, Nopporn
St. Jude Children’s Research Hospital, Physician Scientist Training Program (PSTP) Fellowship - “Chronic worm infections impair immune defenses against pneumococcal pneumonia”

Bagga, Bindiya
Le Bonheur Children's Medical Center Small Grant - "Evaluating immune correlates of Protection and Unrecognized Prolonged Viral Replication in the Pathogenesis of Human Respiratory Syncytial Viral Infection"

Carr, Silvana 
MedImmune Investigator Initiated Research Program (MIIRP) - "A pilot Study of FluMist, an intranasal influenza vaccine in children with cancer"

Hakim, Hana
Infectious Diseases Society of America Travel Grant - "Low Risk Prediction Model for Pediatric Cancer Patients Presenting with Fever and Neutropenia”

Hijano, Diego
University of Tennessee Health Science Center Translational Research Award - “Mucosal dendritic cells in the infant fail to mature in response to early viral infections resulting in reduced IgA”

Hysmith, Nicholas
Southern Society for Pediatric Research (SSPR)/APA Trainee Travel Award
St. Jude Children’s Research Hospital, Physician Scientist Training Program (PSTP) Fellowship

Kamei, Akinobu
Pediatric Infectious Diseases Society - St. Jude Children's Research Hospital Fellowship Award in Basic Research

Khuon, Daliya
Le Bonheur Fellows’ Grant Award

Maron, Gabriela
Merck Young Investigator's Award; Gilead Scholarship Award; IDSA Fellow Grants Program Award

Minniear, Timothy
Young Investigator Award, 16th Conference on Retroviruses and Opportunistic Infections; Fellows Travel Grant, 47th Annual Meeting of the Infectious Diseases Society of America

Mukkada, Sheena
Pediatric Infectious Diseases Society - St. Jude Children's Research Hospital Fellowship Award in Basic Research

St. Jude Children’s Research Hospital, Physician Scientist Training Program (PSTP) Fellowship

Naeem, Fouzia
Le Bonheur Children's Hospital grant for the etiology, prognosis and inflammatory markers in pediatric pneumonia project.

Fellows Travel Grant to attend the 49th Annual Meeting of the Infectious Diseases Society of America (IDSA)

Ramirez, Kacy
Methodist Healthcare Foundation Grant Award ($24,607.50) for:
The molecular quantification of herpes simplex virus (HSV) in the cerebrospinal fluid (CSF) as a predictor of disease severity in neonates, children and adults with encephalitis
July 2011-2013

Southern Society for Pediatric Research (SSPR)/APA Trainee Travel Award
($500), SSPR Annual Meeting, New Orleans, LA
Feb 2012

Southern Society for Pediatric Research (SSPR)/APA Trainee Travel Award
($500), SSPR Annual Meeting, New Orleans, LA

Tanner (Westfall), Mary R.
Children’s Infection Defense Center Grant
Title: Incentives to promote treatment adherence among HIV-infected adolescents

Wolf, Joshua
St. Jude Physician Scientist Training Program (PSTP) Fellowship

The Pediatric Infectious Diseases Fellowship (Subspecialty Residency) Program is an Accreditation Council for Graduate Medical Education (ACGME)-approved program affiliated with the Pediatric Residency Program at the University of Tennessee Health Science Center. The faculty is distributed between the two sponsoring hospitals, Le Bonheur Children's Hospital and St. Jude Children's Research Hospital. The program is a three-year program and is sufficiently flexible to permit trainees to gain expertise in an area of basic or translational science research of their choosing. Participation in M.S. in Epidemiology or Public Health programs is also available. The mission of the Fellowship Program is to prepare outstanding clinicians for a successful career in academic medicine, with an emphasis on training to make scholarly contributions to the field as an independent investigator. It is an expectation that program graduates will provide outstanding clinical care to children and young adults with infectious diseases and will meet the requirements for board certification in Pediatric Infectious Diseases by the American Board of Pediatrics.

AFFILIATED HOSPITAL: St. Jude Children's Research Hospital

AFFILIATED HOSPITAL: Lebonheur Children's Hospital







  • Program provides training in diagnostic microbiology using laboratories on site:
    • Microbiology laboratory
    • Clinical virus isolation laboratory
    • Molecular diagnostics
  • Program provides training in infection control and hospital epidemiology as:
    • Didactic lectures
    • Hands on experience
    • Infection Control Meetings/Membership
  • Opportunity to fulfill the ABP requirements for scholarly activity is available in the following general areas:
    • Bacteriology/bacterial infections
    • Epidemiology and statistics
    • Infection control/hopsital epidemiology
    • Immunizations/Public health
    • Mycology/fungal infections
    • Parasitology/parasitic diseases
    • Virology/viral diseases
    • Antimicrobial agents
  • Research opportunities in the section's program coube described as:
    • Basic (bench)
    • Molecular
    • Community
    • Epidemiologic
    • Clinical
    • International/Public Health
    • Health Services
    • HIV, Basic
    • ACTG Site
  • Documented liaison exists offering opportunities for research experience in the laboratory of investigator(s) who is (are) not faculty of the section: Yes
  • Program offers the opportunity to obtain a Master's degree in a field such as Public Health, Education, Clinical Sciences, or Epidemiology (assuming appropriate arrangements are made): Yes
  • Graduate school courses are available to training (assuming appropriate arrangements are made): Yes
  • Program provides substantial clinical experience for trainees in:
    • HIV
    • Hematopoietic stem cell transplantation
    • Solid organ/transplantation
    • Travelers/adoptees
    • Adults
    • Congenital immune definciencies
  • Program includes ABP-required core curricula in scholarly activities in didactic lecture course for fellows (includes epidemiology, statistics, research design, and academic careers): Yes
  • Prgram has NIH-sponsored training grant: No
  • The Infectious Diseases Service is the primary care provider for HIV infected children and adolescents: Yes
  • Average number of new outpatient consultations per month: 20
  • Average number of established outpatient follow-up visits per month: 150
  • Average number of new inpatient consultations per month: 85
  • Number of trainees completing program in the last 5 years: 10