Brown Medical School / Rhode Island Hospital

593 Eddy Street
Providence
RI
02903
USA
Contact Person: Kathryn Wilson
Phone: (401) 444-8360
Fax: (401) 444-5650

TRAINING PROGRAM DIRECTOR: Penelope H. Dennehy, M.D.

CHIEF OF INFECTIOUS DISEASES: Penelope H Dennehy, MD

RESEARCH INTEREST: Rotavirus vaccine and epidemiology; clinical trials of vaccines and immunobiologics for viral respiratory and gastrointestinal infections

ASSOCIATE: E Jane Carter, MD
RESEARCH INTEREST: Tuberculosis

ASSOCIATE: Kimberle Chapin, M.D.
RESEARCH INTEREST: Viral diagnostics and microbiology

ASSOCIATE: Jennifer F Friedman, MD (International Health)
RESEARCH INTEREST: Malaria and schistosomiasis

ASSOCIATE: Phyllis T Losikoff, MD, MPH
RESEARCH INTEREST: Hepatitis C infection in adolescents

ASSOCIATE: Ian C. Michelow, MBBCh, FCPaed(SA), MMed(Paed), DTM&H             RESEARCH INTEREST: Malaria Vaccines, Viral Infections in Neonates

ASSOCIATE: Leonard A Mermel, HO (Hospital Epidemiologist)
RESEARCH INTEREST: Catheter-related infections; infection control and epidemiology

ASSOCIATE: Boris Skurkovich, MD
RESEARCH INTEREST: International adoption

TITLE(S) OF RECENT FELLOWS' PUBLISHED PAPERS OR RESEARCH PROJECTS:

Kari Simonsen, M.D. (Pediatric ID Fellow 7/1/04-6/30/07)

Simonsen KA, Wang Y, Jiang B, Dennehy PH. Factors Associated with Antigenemia in US Children with Acute Rotavirus Gastroenteritis. 2007 Pediatric Academic Societies’ Meeting (Abstract #754288) (Presented)

Simonsen K, Harwell J, Muriel F, Lainwala S. A Cluster of Transfusion-Associated Babesia microti Infections in Very Low Birth Weight Infants. Platform Presentation. Eastern Society for Pediatric Research Annual Meeting, Philadelphia, PA. March 9-11, 2007.

Simonsen K, Harwell J, Muriel F, Lainwala S. A Cluster of Transfusion-Associated Babesia microti Infections in Very Low Birth Weight Infants. Abstract/Poster presentation. Pediatric Academic Societies Annual Meeting, Toronto, Canada. May 5-8, 2007.

Rutman M, Garro A, Simonsen K, Jaeger JL, Lockhart G. Lyme Disease as a Cause of Aseptic Meningitis in Children in a Lyme-Endemic Region. Abstract/Poster presentation. Society for Academic Emergency Medicine, Chicago, IL May 16-19, 2007.

Simonsen K, Rutman M, Garro A, Lockhart G, Jaeger JL. Lyme Disease as a Cause of Aseptic Meningitis in Children in a Lyme-Endemic Region. Abstract/Poster presentation. Pediatric Academic Societies Annual Meeting, Toronto, Canada. May 5-8, 2007.

Garro A, Simonsen K, Rutman M, Chapin K, Jaeger J, Lockhart G. Prediction of Lyme Meningitis in Children: Validation of Logistic-Regression Model in an Endemic Region. IDSA, 2008 (Washington, DC)

Emily Lutterloh, M.D. (Adult Infectious Disease/Pediatric Infectious Disease Fellow 7/2003-6/30/2007)

Lutterloh E, Opal S, Keith J, Tan X, Clancy B, Kanki K, Palmer H, Wang Q, Pittman D. Administration of antibody against the receptor for advance glycation end products (RAGE) improves survival in the murine model of polymicrobial sepsis. In: Abstracts of the 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; San Francisco, CA, September 27-30, 2006, Abstract 860

Lutterloh E, Opal SM, Pittman DD, Keith JC Jr, Tan XY, Clancy BM, Palmer H, Milarski K, Sun Y, Palardy JE, Parejo NA, Kessimian N. Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection. Crit Care. 2007;11(6):R122.

Lutterloh EC, Opal SM. Antibodies against RAGE in sepsis and inflammation: implications for therapy. Expert Opin Pharmacother. 2007 Jun;8(9):1193-1196.

Nicole Alexander, M.D. (Adult Infectious Disease/Pediatric Infectious Disease Fellow 7/2005-6/30/2009)

Alexander N, Jordan H, Sejvar J, Winchell J, Thurman K, Walter N, Hicks L, Bandy U, Dennehy P: Mycoplasma pnuemoniae Neurological Disease Associated with a Community Respiratory Outbreak. 45th Annual Meeting of IDSA, San Diego, CA (Abstract 213) (Poster)

Walter N, Grant G, Winchell J, Schwartz S, Bandy U, Alexander N, Moore M. Community outbreak of Mycoplasma pneumoniae - Rhode Island, 2006. 45th Annual Meeting of IDSA, Abstract #325. San Diego, CA, October 4-7 (Poster)

Michael Koster, M.D. (Pediatric ID Fellow 7/1/2007- 6/31/2010)

Koster MP, Daigneault L, Dickenson R, Chapin K. Utilization of Rapid PCR Testing for Enterovirus and Impact on Physician Practice. Amer. Society for Microbiology, Boston, MA, 2008 (Poster)

Koster MP, Stellato N, Kohn N, Rubin LG. "Needle Length for Immunization of Adolescents as Determined by Sonographic Measurements." Presented at 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 2007.

Koster MP, Beneri CA, Rajan S, Sood SK. "Three cases of Group A Streptococcal (GAS) Invasive Disease Complicating Influenza in Children During Winter 2006-2007." Presented at 47th Annual Infectious Diseases Society of America Conference (IDSA), San Diego, CA, October 4-7, 2007.

Cranford M, Koster MP, Dickenson R, Dennehy PH, Chapin K. Comparison of Mono vs Multiplex Real-Time PCR Assays for the Detection of Human Bocavirus. 26th Annual Clinical Virology Symposium. 2010

 

Rusty McCulloh (Adult Infectious Disease/Pediatric Infectious Disease Fellow 7/2009-6/30/2013)

Publications

Alverson, B., McCulloh, R., Dawsonb-Hahn, E., Smitherman, S., Koehn, K.  “The Clinical Management of Preterm Infants with Bronchiolitis.” Hospital Pediatrics (in press)

.

McCulloh, R., Opal, S. “Human recombinant lactoferrin for adult sepsis: Too good to be true?”  (Invited commentary).  Critical Care Medicine (in press).

 

McCulloh, R., Alverson, B. “The challenge—and promise—of local clinical practice guidelines.” (Invited commentary).  Pediatrics 2012, 130(5):941-2.

 

McCulloh, R. “Biomarkers in Sepsis and Severe Infection: Where Immunology Meets Diagnostics”.  J Immunodefic Disor 2012, 1:1.

 

McCulloh, R., Smitherman, S., Adelsky, S., Congdon, M., Librizzi, J., Koehn, K., Alverson, B.  “Hospitalist and non-Hospitalist Adherence to Evidence-Based Quality Metrics for BronchiolitisHospitalist and non-Hospitalist Adherence to Evidence-Based Quality Metrics for Bronchiolitis.”  Hospital Pediatrics 2012, 2(1): 21-25.

 

Vyas, D., Mcculloh, R., Dyer, C., Gregory, G., Higbee, D.  “An Interprofessional Course Utilizing Human Patient Simulation to teach Patient Safety and Teamwork Skills.” American Journal of Pharmaceutical Education Vol. 76, Iss. 4 (2012).

 

McCulloh, R., Alverson, B. “Illustrative Case: Lymphadenitis.”  Hospital Pediatrics 2011, 1(1): 52-54.

 

McCulloh, R., Phillips, R., Perfect, J., et. al. “Cryptococcus gattii genotype VGI infection in New England.” Pediatric Infectious Diseases Journal.  2011, Dec; 30(12): 1111-4

 

Chan, P.; Mermel, L.; Andrea, S.; McCulloh, R.; et. al.  “Distinguishing characteristics between pandemic 2009-2010 influenza A (H1N1) and other viruses in patients hospitalized with respiratory illness.”  PLoS One. 2011;6(9):e24734. Epub 2011 Sep 16.

 

Book Chapter

Opal, S., and McCulloh, R.  “Drug-Induced Suppression of the Immune System” (Book Chapter).  From: Oxford Textbook of Critical Care. (in press).

 

Posters

McCulloh, R., Alverson, B., Koehn, K. “Continuous versus intermittent pulse oximetry monitoring of children hospitalized for bronchiolitis.” (poster) Presented at IDWeek 2012 in San Diego, CA.

 

Riese, J., McCulloh, R., Alverson, B. “Investigation of Factors Associated with Hospital Readmission for Bronchiolitis.” (poster).  Presented at Society for Hospital Medicine’s Pediatric Hospital Medicine meeting July 19, 2012 in Cincinatti, OH.

 

McCulloh, R., Alverson, B., Smitherman, S., Koehn, K.  “Comparing responses to albuterol, epinephrine, and steroids among premature and full-term infants with bronchiolitis.” (poster).  Presented at Pediatric Academic Society’s annual meeting April 29, 2012, Boston, MA, and Society for Hospital Medicine’s Pediatric Hospital Medicine meeting July 19, 2012 in Cincinatti, OH.

 

Librizzi, J., McCulloh, R., Alverson, B.  “Appropriateness of Testing for Serious Bacterial Infection in Children Hospitalized with Bronchiolitis” (poster).  Presented at ESPR annual meeting March 30, 2012 in Philadelphia, PA and Society for Hospital Medicine’s Pediatric Hospital Medicine meeting July 19, 2012 in Cincinatti, OH.

 

McCulloh, R., Dyer, C., Gregory, G., Higbee, D., Vyas, D.  “Utilizing Interprofessional Simulation for Teamwork and Safety Learning in Undergraduate and Graduate Medical Education.”  (Workshop).  To be presented at Pediatric Academic Society’s annual meeting April 29, 2012, Boston, MA.

 

Dyer, C., Gregory, G., Higbee, D., Vyas, D., McCulloh, R. “The Effect of Interprofessional Simulation on Teamwork and Safety Learning for Healthcare Students” (platform presentation) Presented at the Association of Standardized Patient Educators annual meeting June 6, 2011 in Nashville, TN.

 

McCulloh, R., Smitherman, S., Adelsky, S., Congdon, M., Librizzi, J., Koehn, K., Alverson, B.  “Practice Differences of Hospitalists vs Non-Hospitalists in Bronchiolitis: A Multi-Center Study” (poster).  Presented at the Pediatric Academic Society annual meeting April 30, 2011, Denver, CO.

 

McCulloh, R., Smitherman, S., Adelsky, S., Congdon, M., Librizzi, J., Koehn, K., Alverson, B.  “Practice Differences of Hospitalists vs Non-Hospitalists in Bronchiolitis: A Multi-Center Study” (platform presentation).  To be presented at the Pediatric Hospital Medicine Annual Meeting annual meeting July 28, 2011 in Kansas City, MO.

 

Smitherman, S., McCulloh, R., Alverson, B., Koehn, K.  “Bronchiolitis Practice Management before and after AAP Guidelines in 2006” (poster).  Presented at the Pediatric Academic Society’s annual meeting April 30, 2011 in Denver, CO.

 

Smitherman, S., McCulloh, R., Alverson, B., Koehn, K.  “Bronchiolitis Practice Management before and after AAP Guidelines in 2006” (poster).  To be presented at the Pediatric Hospital Medicine Annual Meeting annual meeting July 28, 2011 in Kansas City, MO.

 

McCulloh, R., Smitherman, S., et. al.  “Hospitalists better adhere to evidence-based guidelines for inpatient bronchiolitis management: results from a multi-center study” (platform presentation) Presented at ESPR, March 27, 2011, Philadelphia, PA.

 

Adelsky, S; McCulloh, R.; Koehn, K., Alverson, B.  “Practice management changes before and after 2006 American Academy of Pediatrics guidelines for acute bronchiolitis diagnosis and treatment.”  (poster) Brown University Alpert School of Medicine Student Poster Showcase.

 

McCulloh, R.; Andrea, S.; Dennehy, P.; Chapin, K.  “Implementation of a multiplex PCR respiratory viral panel (RVP) assay in a tertiary care setting: insights gained on viral epidemiology and the effect on physician antiviral prescription practices” IDSA annual meeting, October, 2010.

 

Brian Chow (Adult Infectious Disease/Pediatric Infectious Disease Fellow 7/2010-6/30/2014)

Publications

B.D.W. Chow, J.R. Linden, J.M. Bliss.  “Candida parapsilosis and the Neonate: Epidemiology, Virulence and Host Defense in a Unique Patient Setting.” Expert Reviews of Anti Infective Therapy. 10(8), 935-946 (2012).

 

Abstracts

B.D.W. Chow,  E.O Perry, J.M. Bliss. The role of expressed breast milk on colonization of neonates with Candida species. Pediatric Infectious Diseases Society/St. Jude’s.  Memphis, TN. February 2012.

 

B.D.W. Chow,  E.O Perry, J.M. Bliss. The role of expressed breast milk in colonization of neonates with Candida species. ID Week, October 2012.  San Diego, CA.

 

Tanya Rogo (Pediatric Infectious Disease Fellow 7/2010-6/30/2013)

Publications

N. Alexander, P.A. Chan, T. Rogo, Z. Parillo, C.A. Browning, C. Calcione, S. Chowdhury, P. Simon, R. Kantor . Interrupting Transmission of HIV and other Sexually Transmitted Infections in Rhode Island. Medicine and Health Rhode Island 2012 Aug;95(8):241-244.

 

Abstracts

T. Rogo, A.K. Delong, P.A. Chan,  R. Kantor. High levels of Diversity and Drug resistance in the only Pediatric HIV Clinic in Rhode Island. October 19 2012, IDWeek 2012, San Diego, CA

 

T. Rogo, A.K. Delong, P.A. Chan,  R. Kantor. High levels of Diversity and Drug resistance in the only Pediatric HIV Clinic in Rhode Island. October 11 2012, Lifespan Annual Research Celebration, Providence, RI

 

Susanna Winston (Pediatric Infectious Disease Fellow 7/2011-6/30/2014)

Abstracts

Winston SE, Montague BT, Lopez MJ, DeLong A, LeMarchand, C, Bedoya A, Gillani FS, Beckwith CG.  Evaluation of longitudinal clinical outcomes and adherence to care among HIV-infected refugees. J Int Assoc Physicians AIDS Care (Chic). 2012 Sep 28 [Epub ahead of print]

 

Winston SE and Beckwith CG. The Impact of Removing the Immigration Ban on HIV Infected Persons.  AIDS Patient Care and STDs. 2011 Dec;25(12):709-11.

 

Publications

Winston  SE, Chirchir AK, Muthoni LN, Ayuku D, Koech J, Nyandiko W, Carter EJ and Braitstein P.  Sexually Transmitted Infections among Street Involved Youth in Eldoret, Kenya abstract #0314.  10th World Congress of the International Association for Adolescent Health.  June 2013.  [accepted for poster]

 

Winston  SE, Chirchir AK, Muthoni LN, Ayuku D, Koech J, Nyandiko W, Carter EJ and Braitstein P.  Sexual Risk and HIV Prevalence in Street-Involved Youth in Western Kenya. Poster #1040, Knowledge, Attitudes, Screening and Prevention session, on Oct 19th, 2012.  IDWeek 2012, San Diego, CA.  Oct 17-21, 2012.

 

Natasha Rybak (Adult Infectious Disease/Pediatric Infectious Disease Fellow 7/2012-6/30/2016)

LaCourse, S, Rybak, N, Larkin, J and Lewis, C. Health Screening of Refugees in Providence, RI. Abstract Poster # 30927. Presented at the 49th Annual Infectious Disease Society of America. ID Week. Boston, MA. October 20-23 2011.

 

 

Chan PA, Mermel LA, Andrea SB, McCulloh R, Mills JP, Echenique I, Leveen E, Rybak N, Cunha C, Machan JT, Healey TT, Chapin KC.  Distinguishing Characteristics between Pandemic 2009-2010 Influenza A (H1N1) and Other Viruses in Patients Hospitalized with Respiratory Illness. PLoS One. 2011;6(9):e24734. Epub 2011 Sep 16.

 

MAJOR FEATURES OF TRAINING PROGRAM: The goals of this program are acquisition of clinical experience and expertise in pediatric infectious diseases, fostering of skills as an educator, and development of competence to subsequently undertake independent investigation demonstrated by meaningful accomplishment in research during fellowship. The first year is primarily clinical, and includes active participation in monthly pediatric infectious disease conferences and an elective in diagnostic microbiology, and approximately 8 months on the pediatric infectious disease inpatient and ambulatory services. The primary commitment in the first year is to the development of clinical skills and competence in the subspecialty. In the second year, development of investigative capabilities is emphasized and the fellow is expected to pursue one or more research projects in depth. In the third year, the fellow devotes most of his/her time to research. Opportunities include laboratory, epidemiological, and clinical studies in infectious diseases and related disciplines in the various departments at Brown-affiliated hospitals and on-campus, including the International Health Institute. Brown faculty are currently working on projects in Cambodia, the Philippines and Kenya . Med/Peds combined infectious diseases fellowship training is available.

AFFILIATED HOSPITALS: Women and Infants Hospital of Rhode Island

NUMBER OF PEDIATRIC BEDS: 160

FELLOWS ACCEPTED EACH YEAR: 1

TRAINING FOR MD; DO; MD, PhD: MD

FUNDING IS ENSURED FOR ALL 3 YEARS: Yes

VISAS ACCEPTED: J1

IS COMPLETION OF PEDIATRIC RESIDENCY TRAINING IN THE U.S. OR CANADA A REQUIREMENT? YES

THE PROGRAM OFFERS THE FOLLOWING TRAINING:

Program provides training in diagnostic microbiology using laboratories on site:

Microbiology laboratory: YES
Clinical virus isolation laboratory: YES
Molecular diagnostics: YES
Other – Please specify:

Program provides training in infection control and hospital epidemiology as:

Didactic lectures: YES
Hands on experience: YES
Infection Control Meetings/Membership: YES

Opportunity to fulfill the ABP requirements for scholarly activity is available in the following general areas:

Bacteriology/bacterial infections: YES
Epidemiology and statistics: YES
Infection control/hospital epidemiology: YES
Immunizations/Public health: YES
Mycology/fungal infections: NO
Parasitology/parasitic diseases: YES
Virology/viral diseases: YES
Antimicrobial agents: YES
Other – Please specify: Research opportunities in the section’s program could be describes as: Basic (bench): YES
Molecular: YES
Translational: YES
Epidemiologic: YES
Clinical: YES
International/Public Health Services: YES
HIV, Basic: YES
HIV, Clinical: YES
ACTG Site: NO
Other – Please specify: Documented liaison exists offering opportunities for research experience n the laboratory of investigator(s) who is (are) not faculty of the section: Yes

Program offers the opportunity to obtain a Master’s degree in a field such as Public Health, Education, Clinical Sciences, or Epidemiology (assuming appropriate arrangements are made): YES
Other – Please specify: Graduate school courses are available to trainee (assuming appropriate arrangements are made): YES

Program provides substantial clinical experiences for trainees in special areas/hosts: HIV: YES
Bone marrow transplantation: NO
Solid organ/transplantation: NO
Travelers/adoptees: YES
Adults: YES
Congenital immune deficiencies: NO
Other – Please specify:

Program includes ABP-required core curricula in scholarly activities in didactic lecture course for fellows (includes epidemiology, statistics, research design, and academic careers): YES

Program has an NIH-sponsored training grant: NO

The Infectious Diseases Service is the primary care provider for HIV-infected children and adolescents: YES

Average number of new outpatient consultations per month: 26

Average number of established outpatient follow-up visits per month: 19

Average number of new inpatient consultations per month: 41

Number of trainees completing program in the last 5 years: (2006-2011) 5