State University of New York Downstate Medical Center

450 Clarkson Avenue
Brooklyn
NY
11203-2098
USA
Phone: (718) 270-3097
Fax: (718) 270-1985

TRAINING PROGRAM DIRECTOR/DIVISION DIRECTOR: Margaret R Hammerschlag, MD
RESEARCH INTERESTS: Chlamydia infections, including C. trachomatis and C. pneumoniae, dx and management of STDs in children, rx MRSA infections

ASSOCIATE DIRECTOR: Stephan A. Kohlhoff, MD
RESEARCH INTEREST: C. pneumoniae infection and asthma, disaster preparedness, antibiotic stewardship

ASSOCIATE: Hermann Mendez, MD
RESEARCH INTERST: HIV in children

ASSOCIATE: Matt Gesner, MD
RESEARCH INTERST: HIV in children; Kawasaki disease

ASSOCIATE: Tamar Smith-Norowitz, PhD
RESEARCH INTEREST: Infection and asthma

TITLE(S) OF RECENT FELLOWS' PUBLISHED PAPERS OR RESEARCH PROJECTS:

  1. Nathawad R, Mendez H, Ahmad A, Laungani S, Hoa B-T, Garlick J, Hammerschlag MR. Severe ocular reactions after neonatal ocular prophylaxis with gentamicin ophthalmic ointment. Pediatr Infect Dis J 30:175-176, 2011.
     
  2. Chotikanatis K, Backer M, Rosas-Garcia G, Hammerschlag MR. Recurrent intravascular catheter-related bacteremia caused by Delftia acidovorans in hemodialysis patient. J Clin Microbiol 49:3418-3421, 2011.
     
  3. Nathawad R, Gesner M, Kohlhoff SA, Hammerschlag MR. Management of bone and joint infections in children: recent experience at an urban medical center. Infect Dis Clin Prac. 20:49-52, 2012.
     
  4. Nathawad R, Hammerschlag MR, Mendez HA. Colonization with Staphylococcus aureus in HIV-infected children and adolescents in Brooklyn, NY. J Pediatr Infect Dis 7:97-102, 2012.
     
  5. Dzhindzhikhashvili M, Joks R. Smith-Norowitz, T, Durkin H, Chotikanatis K, Estrella E, Hammerschlag M, Kohlhoff S. Doxycycline suppresses Chlamydia pneumoniae mediated increases in ongoing IgE and IL-4 responses by peripheral blood mononuclear cells of patients with allergic asthma. J Antimicrob Chemother, in press 2013.
     
  6. Chotikanatis K, Hammerschlag MR, Kohlhoff SA. Impact of universal Chlamydia trachomatis (CT) screening during pregnancy on pediatric CT seroprevalence: 1991-2011 cohort study. Presented at the 50th annual Meeting of the Infectious Diseases Society of America, San Diego, CA, October 17-21, 2012.
     
  7. Chotikanatis K, Weaver D, Lent D, Estrella E, Hammerschlag MR, Joks RO, Kohlhoff SA. Chlamydia pneumoniae - induced in vitro interferon gamma and interleukin 2 Responses of PBMC from asthmatics.  Presented at the AAAAI Annual Meeting, San Antonio, TX, February 22-26, 2013.
     
  8. Chotikanatis K, Weaver D, Estrella E, Hammerschlag MR, Joks Ro, Kohlhoff SA. In Vitro tumor necrosis factor alpha responses to Chlamydia pneumoniae infection of PBMC from asthmatics. Presented at the Annual Meeting of the Pedatric Academic Societies, Washington, DC, May 4-7, 2013.
     
  9. Arun A, Sharma R, Kohlhoff S, Hammerschlag MR. Cancomycin minimum inhibitory concentration (MIC) creep in methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections in children seen in an urban medical center.  Presented at the Annual Meeting of the Pediatric Academic Societies, Washington, DC, May 4-7, 2013.
     
  10. Aparna Arun Sudhindra Pydimarri, Kobkul Chotikanatis, Roopali Sharma, Stephan Kohlhoff.  Bacteremia in Pediatric Patents - Clinical Outcome Correlates with the Antimicrobial Management Score (AMS). Presented at the Annual Meeting of the Pediatric Academic Societies, Washington, DC, May 4-7, 2013.
     
  11. Chotikanatis K, Kohlhoff SA, Hammerschlag MR. In vitro activities of nemonoxacin, a novel quinolone antibiotic, against Chlamydia pneumoniae. Presented at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy, Denver, CO, September 10-13, 2013. 

GRANT FUNDING RECEIVED FOR FELLOW RESEARCH PROJECTS:

Dr. Chotikanatis: Dean's Research Initiative 2010

Dr. Kohlhoff: 2012 New York State ECRIP Fellowship

MAJOR FEATURES OF TRAINING PROGRAM: The program offers a broad experience in pediatric infectious diseases in a large inner-city medical center that serves a very diverse population. There is also a rotation on the adult ID service, joint conferences and rounds. We provide experience with common infectious diseases, but as the major academic medical center in Brooklyn we also see many unusual disease entities. We offer opportunities to do research in chlamydial infections, STDs, hospital acquired infections and antibiotic resistance and HIV. There are opportunities to work with basic science departments, especially microbiology and immunology. Fellows will have a total of 12 months of clinical service including one monthly on the adult ID service, and 24 months of research.

AFFILIATED HOSPITALS: University Hospital of Brooklyn, Kings County Hospital Center

NUMBER OF PEDIATRIC BEDS: 100, NICU: 60

FELLOWS ACCEPTED EACH YEAR: 1

TRAINING FOR MD; DO; MD, PhD: MD or DO

FUNDING IS ENSURED FOR ALL 3 YEARS: YES

VISAS ACCEPTED: J1, Other

IS COMPLETION OF PEDIATRIC RESIDENCY TRAINING IN THE U.S. OR CANADA A REQUIREMENT? NO

THE PROGRAM OFFERS THE FOLLOWING TRAINING:

Program provides training in diagnostic microbiology using laboratories on site:

Microbiology laboratory: YES
Clinical virus isolation laboratory: YES
Molecular diagnostics: YES
Other – Please specify: Chlamydia

Program provides training in infection control and hospital epidemiology as:

Didactic lectures: YES
Hands on experience: YES
Infection Control Meetings/Membership: YES

Opportunity to fulfill the ABP requirements for scholarly activity is available in the following general areas:

Bacteriology/bacterial infections: YES
Epidemiology and statistics: YES
Infection control/hospital epidemiology: YES
Immunizations/Public health: YES
Mycology/fungal infections: NO
Parasitology/parasitic diseases: NO
Virology/viral diseases: YES
Antimicrobial agents: YES
Other – Please specify:

Research opportunities in the section’s program could be describes as:

Basic (bench): YES
Molecular: YES
Translational: YES
Epidemiologic: YES
Clinical: YES
International/Public Health: YES
Health Services: YES
HIV, Basic: NO
HIV, Clinical: YES
ACTG Site: YES
Other – Please specify:

Documented liaison exists offering opportunities for research experience n the laboratory of investigator(s) who is (are) not faculty of the section: YES

Program offers the opportunity to obtain a Master’s degree in a field such as Public Health, Education, Clinical Sciences, or Epidemiology (assuming appropriate arrangements are made): YES, specifically MPH from the SUNY Downstate School of Public Health

Other – Please specify:

Graduate school courses are available to trainee (assuming appropriate arrangements are made): YES

Program provides substantial clinical experiences for trainees in special areas/hosts:

HIV: YES
Bone marrow transplantation: NO
Solid organ/transplantation: YES
Travelers/adoptees: YES
Adults: YES
Congenital immune deficiencies: YES
Other – Please specify: Sickle cell disease

Program includes ABP-required core curricula in scholarly activities in didactic lecture course for fellows (includes epidemiology, statistics, research design, and academic careers): YES

Program has an NIH-sponsored training grant: NO

The Infectious Diseases Service is the primary care provider for HIV-infected children and adolescents: YES

Average number of new outpatient consultations per month: 10

Average number of established outpatient follow-up visits per month: 20

Average number of new inpatient consultations per month: 30

Number of trainees completing program in the last 5 years (2002-2003)