Stanford University School of Medicine

Department of Pediatrics, 300 Pasteur Drive G312
Stanford
CA
94305-5208
USA
Phone: (650) 723-5682
Fax: (650) 725-8040

TRAINING PROGRAM DIRECTOR: Sruti Nadimpalli, MD, MPH

ASSOCIATE TRAINING PROGRAM DIRECTOR: Hayley Gans, MD
RESEARCH INTERESTS: Measles virus; T and B-cell immunity in infants immunized with measles and mumps vaccine; ontogeny of infant immune response to viral vaccines; primary immunodeficiency


ASSOCIATE: Manuel Amieva, MD, PhD 
RESEARCH INTEREST: Bacterial pathogensis, helicobacter

VICE PROVOST AND DEAN OF RESEARCH: Ann M Arvin, MD
RESEARCH INTERESTS: Varicella-zoster virus: molecular virology; pathogenesis of infection; T-cell immunity to viral proteins; herpes virus vaccines;developmental immunology-adaptive T cell immunity to viral pathogens and vaccines in infants and young children

ASSOCIATE: Sharon Chen, MD
RESEARCH INTEREST: Viral Immunity in transplant patients

ASSOCIATE: Cornelia L Deckker, MD
RESEARCH INTEREST: Vaccine clinical research; vaccine safety; immunology of herpesvirus infections; antiviral therapies

ASSOCIATE: Kathleen Gutierrez, MD
RESEARCH INTERESTS: Neonatal HSV infection; pediatric HIV infection; antiviral therapy, Epidemiology of Influenza and MRSA

ASSOCIATE: David B Lewis, MD
RESEARCH INTERESTS: Developmental immunobiology of T cells, Influenza vaccines, transplant immunology

CHIEF OF INFECTIOUS DISEASES: Bonnie Maldonado, M.D.
RESEARCH INTERESTS: Varicella-zoster virus: molecular virology; pathogenesis of infection; T-cell immunity to viral proteins; herpes virus vaccines;developmental immunology-adaptive T cell immunity to viral pathogens and vaccines in infants and young children

SENIOR ASSOCIATE DEAN OF MEDICAL SCHOOL EDUACTION: Charles G Prober, MD
RESEARCH INTERESTS: Epidemiology of HSV infections; antiviral therapy; antimicrobial pharmacology in children; clinical trials

TITLE(S) OF RECENT FELLOWS’ PUBLISHED PAPERS OR RESEARCH PROJECTS: Nakamura F, Huang L, Pestonjamasp K, Amieva MR, Luna E, Futhmayer H. Threonine 558 phosphorlation of moesin in human platelets activates F-actin by exposing cryptic site. Molecular Biology of the Cell, 1998.9 (Suppl):P.268A. Amieva MR, Litman P, Huang L, Tchimaru F, Furthmayer H. Disruption of dynamic cell surface architecture of HIH3T3 fibroblasts by the N-terminal domains of moesin and ezrin: In vivo imaging with GFP proteins. Journal of Cell Science, 1999 Jan 112 (Pt 1): 111-25. Cron RQ, Bartz SR, Clausell AL, Bort SJ, Lewis DB. NFATI enhances HIV-1 gene expression in normal human CD4 T cells. Clin Immunology 94:179-191,2000. Cron RQ, Bort SJ, Wang Y Brunyand M, Lewis DB. T cell priming enhances IL-4 gene expression by increasing NFAT. J Immunol 162:862-870, 1999. Gans H, Maldonado Y, Yasukawa LL, Beeler J, Rinki MM, DeHovitz R, Arvin AM. Interleukin 12, Interferon, and T cell proliferation to measles in immunized Infants. The Journal of Immunology:162(9):5569-75, 1999.

MAJOR FEATURES OF TRAINING PROGRAM: The program is designed to train fellows for careers in academic medicine, with an emphasis on both clinical and laboratory traning. Intensive training in both clinical and laboratory research is a emphasis, with focus on learning techniques of immunology, molecular biology and pathogenesis as applied to studies of human viral and bacterial disease and the host response to viral infection. Fellows spend a total of 12 months on the clinical service during a three to four year training period, and participate in teaching activities when on service. The clinical service includes interaction with medical students, pediatric and surgical residents and attendings. Each fellow also is expected to plan and carry out a scholarly project with significant merit, including clinical, translational or laboratory research projects. Collaborative research and teaching activities exist with the Department of Microbiology/Immunology and Medicine, Division of Infectious Diseases, and Geographic Medicine. The option of a fourth year in the lab. is encouraged for some fellwos wishing to obtain sufficient experience in laboratory research.  The clinical experience is broad including infectious diseases of otherwise healthy children, as well as infections in children with chronic and/or immunosuppressive disorders. Clinical training is at the Lucile Packard Children’s Hospital at Stanford.

AFFILIATED HOSPITALS: Lucile Packard Children’s Hospital at Stanford. 
 
NUMBER OF PEDIATRIC BEDS: 264

FELLOWS ACCEPTED EACH YEAR: 1-2
 
TRAINING FOR MD; DO; MD, PhD: Yes

FUNDING IS ENSURED FOR ALL 3 YEARS: Yes

VISAS ACCEPTED: None
IS COMPLETION OF PEDIATRIC RESIDENCY TRAINING IN THE U.S. OR CANADA A REQUIREMENT? Yes

THE PROGRAM OFFERS THE FOLLOWING TRAINING:

Program provides training in diagnostic microbiology using laboratories on site:

Microbiology laboratory:  YES
Clinical virus isolation laboratory: YES
Molecular diagnostics: YES
 
Program provides training in infection control and hospital epidemiology as:
 
Didactic lectures:  YES
Hands on experience: YES
Infection Control Meetings/Membership: NO
 
Opportunity to fulfill the ABP requirements for scholarly activity is available in the following general areas:
 
Bacteriology/bacterial infections: YES
Epidemiology and statistics: YES
Infection control/hospital epidemiology: YES
Immunizations/Public health: YES
Mycology/fungal infections: YES
Parasitology/parasitic diseases: YES
Virology/viral diseases: YES
Antimicrobial agents: YES

 
Research opportunities in the section’s program could be describes as:
 
Basic (bench): YES
Molecular: YES
Translational: YES
Epidemiologic: YES
Clinical: YES
International/Public Health: YES
Health Services: NO
HIV, Basic: YES
HIV, Clinical: YES
ACTG Site: YES

 
Documented liaison exists offering opportunities for research experience n the laboratory of investigator(s) who is (are) not faculty of the section: YES
 
Program offers the opportunity to obtain a Master’s degree in a field such as Public Health, Education, Clinical Sciences, or Epidemiology (assuming appropriate arrangements are made): YES
 
Other – Please specify:
 
Graduate school courses are available to trainee (assuming appropriate arrangements are made): YES
                                 
Program provides substantial clinical experiences for trainees in special areas/hosts:
 
HIV: YES
Bone marrow transplantation: YES
Solid organ/transplantation: YES
Travelers/adoptees: YES
Adults: NO
Congenital immune deficiencies: YES
 
Program includes ABP-required core curricula in scholarly activities in didactic lecture course for fellows (includes epidemiology, statistics, research design, and academic careers): YES
 
Program has an NIH-sponsored training grant: NO
 
The Infectious Diseases Service is the primary care provider for HIV-infected children and adolescents: YES
 
Average number of new outpatient consultations per month: 15
 
Average number of established outpatient follow-up visits per month: 34

Average number of new inpatient consultations per month: 31

Number of trainees completing program in the last 5 years: (2002-2007): 6